Lyn Armit - First National - Ipswich

Lyn constitutively phosphorylates PIR-B to recruit and activate SHP-1 (88 Similarly, Lyn is also pro-apoptotic in eosinophils, with Lyn-- mice

Lyn is the predominantly expressed SFK in B cells and has both positive and negative regulatory roles in BCR-induced signal transduction

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lynking88 There are other direct links between Lyn and BCR-Abl signaling pathways as Lyn phosphorylates the Y177 motif of BCR-Abl , resulting in