p62SQSTM1: 'Jack of all trades' in health and cancer

p62SQSTM1: 'Jack of all trades' in health and cancer p62 com The p62 protein, also called sequestosome 1 , is a ubiquitin-binding scaffold protein that colocalizes with ubiquitinated protein aggregates in many p62com In this mechanism, p62 serves as a shuttling protein for ubiquitinated substrates to the proteasome Under stress, the binding increases through the involvement

p62com p62-gels are not simple substrates for autophagy but serve as platforms for both autophagosome formation and anti-oxidative stress

p62 ทางเข้าสล็อต Dusquetide modulates innate immune response through binding to p62 · PubMed: 35640615 Search on PubMedSearch on PubMed Central · Primary SQSTM1 then interacts with ATG8 family proteins on autophagosomes via its LIR motif, leading to p62 body recruitment to autophagosomes, followed by autophagic