Autophagy Impairment in App Knock-in Alzheimer's Model Mice

p62 improves AD-like pathology by increasing autophagy p62 app p62 acts as a selective autophagy receptor that recognizes and shuttles ubiquitinated proteins to the autophagosome for degradation p62com สล็อต Collectively, our data suggest that the downregulation of SEPTIN5 increases the autophagy-mediated degradation of APP CTFs, leading to reduced levels of Aβ in

p62 app Download scientific diagram Only Dutch APPPS1DE9 mice accumulate insoluble p62 from publication: Effective anti-Alzheimer A therapy involves depletion of